The Nutrition-Sleep-Circadian Axis in Age-Related Neurodegeneration: Cellular Mechanisms, Metabolic Dysfunction, and Neuroprotective Interventions.
Advanced age is accompanied by progressive metabolic, nutritional, mitochondrial, and neuroimmune dysregulation, which may increase susceptibility to neurodegenerative disorders such as Alzheimer's disease (AD) and Parkinson's disease (PD), highlighting the need to identify modifiable mechanisms that influence disease...