K. Kamei

Reverse bioengineering of the liver: developmental principles for next-generation liver-on-a-chip systems

Despite major advances in liver-on-a-chip and organoid technologies, most current in vitro liver models remain limited. Here, it is argued that these limitations are fundamentally conceptual rather than purely technical. Reverse bioengineering is introduced as a unifying design framework for liver-on-a-chip systems, in...