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K. Katisko

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Open access Sep 2026

Non-motor symptoms questionnaire-based profiles in early-stage dementias: A prospective cohort study.

BackgroundCurrent knowledge regarding the nature and prevalence of non-motor symptoms across different types of dementia is limited. While Alzheimer's disease (AD), behavioral variant frontotemporal dementia (bvFTD), and dementia with Lewy bodies (DLB) are primarily characterized by cognitive and motor symptoms, severa...

Mika Kinnunen, Emma Vitikka, Johanna Krüger et al. · 0 citations
Open access Aug 2026

C9orf72-associated and sporadic FTD patient iPSC-microglia show differences in phagocytosis and gene expression

Summary C9orf72 hexanucleotide repeat expansion (C9-HRE) is a major genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia (FTD). However, approximately half of the FTD patients are sporadic without a clear genetic background. To compare characteristics of microglia from different FTD subtypes, we g...

Hannah Rostalski, Tomi Hietanen, Dorit Hoffmann et al. · 1 citation

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