K. Kendler

Rare copy number variation in Post-traumatic stress disorder using whole genome sequencing and biobank data

Network analysis of the genetic relationships between twenty psychiatric and substance use disorders

Compared to standard factor analytic methods, network analyses can provide both confirmatory results and novel insights into the structure of genetic risks for a variety of psychiatric disorders.

Distinguishing different psychiatric disorders using DDx-PRS

Despite great progress on case–control polygenic prediction, an unmet need remains for a method that genetically distinguishes clinically related disorders (e.g., schizophrenia (SCZ) versus bipolar disorder (BIP) versus major depressive disorder (MDD) versus controls). We introduce differential diagnosis–polygenic risk...

Elucidating psychosocial outcome profiles as a function of aggregate genetic risk for suicide attempt and alcohol use disorder

It is indicated that aggregate genetic risk profiles for AUD and SA are differentially correlated with a range of negative psychosocial outcomes, underscore the imperative for further genetic dissection of these frequently comorbid conditions.