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Open access Sep 2026

Increasing burden of multiple long-term conditions and mortality risk following COVID-19 diagnosis: a national cohort study of one million adults with cardiovascular disease in England.

BACKGROUND Individuals with cardiovascular disease (CVD) experienced high mortality during coronavirus disease 2019 (COVID-19), yet most live with multiple long-term conditions (MLTCs). We examined the association between MLTCs burden and mortality following COVID-19 among people with CVD. METHODS In this population-...

Yogini V. Chudasama, S. Shabnam, K. Khunti et al. · 0 citations
Aug 2026

Association of Lipid Ratios With Cardiovascular Outcomes in Type 2 Diabetes: A Population Cohort Study.

AIMS To identify low- and high-risk intervals for major adverse cardiovascular events (MACE) and all-cause mortality according to lipid ratios in adults with Type 2 diabetes mellitus (T2DM), stratified by sex. MATERIALS AND METHODS We used primary care electronic health records from the Spanish National Health Servic...

E. Carretero-Anibarro, J. Quesada, Manuel A. Ruiz-Quintero et al. · 0 citations
Review Open access Jul 2026

Comparative effects of drugs for adults with overweight or obesity: systematic review and network meta-analysis

Moderate to high certainty evidence supports discontinuation of drugs for adults with overweight or obesity because of adverse events to be highest with orforglipron, naltrexone-bupropion, liraglutide, phentermine-topiramate, CagriSema, and oral semaglutide.

Kai-Lei Nong, Qingyang Shi, Xinran Xie et al. · 5 citations

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