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K. Kulcenty

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Review Open access Oct 2026

Histone Lactylation in Cancer: Linking Hypoxia-Driven Metabolism to Epigenetic Regulation

Solid tumors are frequently characterized by hypoxia, which drives metabolic reprogramming toward glycolysis and increased lactate production. Beyond its role as a metabolic end product, lactate can influence gene regulation through histone lactylation, a recently identified post-translational modification linking cell...

Julia Ostapowicz, K. Kulcenty · 0 citations

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