Design, Synthesis, Characterization and Pharmacological Evaluation of Novel Imidazole-Based Oxazolone Derivatives as Potential Analgesic and Anti-Inflammatory Agents
Most oxazolone derivatives demonstrated dose- and time-dependent analgesic activity, with OXA03, OXA05, OXA07, and OXA09 showing the strongest effects, in some cases comparable to or exceeding standard drugs (indomethacin and diclofenac).