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Author

K. Kwan

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Open access Sep 2026

Persistent Zn2+ Influx‐Mediated Deacetylation of ANXA2 Regulates the “Zn2+‐Autophagic Flux” and Alleviates Intervertebral Disc Degeneration

ABSTRACT Intervertebral disc degeneration (IVDD) is an age‐related disease accompanied by disrupted mitochondrial homeostasis and defective autophagy. Cellular senescence induces ion imbalance, which leads to mitochondrial damage and suppressed autophagic flux; nevertheless, the molecular mechanism underlying this proc...

Yu-Xin Jin, Yong-Cheng Chen, Yi-Hao Xie et al. · 0 citations
Open access Aug 2026

What is the minimum effective wearing dosage of orthotic intervention in adolescent idiopathic scoliosis?

PURPOSE This study aimed to estimate the minimum effective orthosis-wearing time (MEWT) needed to prevent curve progression and reduce surgical risk in adolescent idiopathic scoliosis (AIS). METHODS This retrospective study analyzed 281 patients with AIS who completed orthotic treatment. Compliance was measured using...

Shan Liu, Babak Hassan Beygi, K. Kwan et al. · 0 citations

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