Introduction.
Cholangiocarcinoma (CC) is one of the most aggressive malignant tumors of the hepatobiliary tract with a poor prognosis, especially at the late stages. The targeted therapy with pemigatinib, a selective FGFR2 inhibitor, can be administered in a proportion (10–15%) of patients with intrahepatic cholangi...
M. Khagazheeva, A. R. Zaretsky, A. N. Koshmanova et al.· Meditsinskiy sovet = Medical...· 0 citations
INTRODUCTION
In ADAURA, adjuvant osimertinib improved DFS and OS versus placebo in resected EGFR-mutated stage IB-IIIA NSCLC. We report a post hoc exploratory analysis of long-term OS post-adjuvant treatment completion.
METHODS
Patients (N = 682) were randomized to osimertinib or placebo until recurrence, treatment c...
Yi-Long Wu, M. Majem, T. John et al.· Journal of Thoracic Oncology· 1 citation
On January 27, 2026, an Advisory Board was held to discuss issues of molecular genetic diagnosis of the BRAF V600E mutation in patients with advanced non-small cell lung cancer (NSCLC), as well as current treatment options for NSCLC patients with the BRAF V600E mutation. Next generation sequencing (NGS) is the most sen...
K. Laktionov, V. Breder, I. A. Demidova et al.· Malignant tumours· 0 citations
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