Author

K. Landfester

3 papers indexed here

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Open access Sep 2026

Sequence-encoded hexagonal lattices in multichannel peptide nanofibrils

Structural complexity in biological matter arises from molecular information that encodes supramolecular assembly across length scales1, 2–3. Here we show that minimal nine-residue peptides can encode discrete lateral interaction motifs that direct supramolecular organization. These motifs generate hexagonal pores and...

Jasmina Gačanin, Francesca Mazzotta, Luis A. Baptista et al. · Nature · 0 citations

Open access Sep 2026

Functional mapping and engineering of the Sec translocon unlocked by a cell-free system

Almost all membrane proteins are inserted or translocated across membranes by the universally conserved Sec translocon. Despite its central role, experimental access to Sec function has remained limited. Here, we present ProSecCO (Protein Secretion in Cell-free via synthetic Operons), which is a cell-free protein synth...

M. Meier, Scott A. Scholz, Leo von Bank et al. · Science Advances · 2 citations

Aug 2026

Cholesterol-Mediated Protein Corona Controls in Vivo Clearance and Selective Organ Distribution of Liposomes

Cholesterol is a key determinant of membrane stability and fluidity in both natural and synthetic lipid systems. Although widely used, its content varies greatly among commercial liposomes, and its regulatory effects on biological interactions remain insufficiently understood. Here, we reveal that cholesterol content...

Fangqin Fu, Yuting Ge, Xuemei Hu et al. · ACS Nano · 0 citations