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Open access Oct 2026

Germline-Somatic Interplay Shapes Molecular Divergence in Peripheral Nerve Sheath Tumors.

Peripheral nerve sheath tumors (PNSTs) arising in neurofibromatosis type 1 (NF1) show marked histological and clinical heterogeneity, ranging from benign to malignant PNSTs. Although germline NF1 variants underlie tumor predisposition, the mechanisms driving phenotypic and clinical heterogeneity remain incompletely def...

Yurimi Lee, Ji-Young Song, Sung-Bin An et al. · 0 citations

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