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K. Liu

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Open access Aug 2026

rRNA 5'ETS processing contributes to nucleolar organization and nuclear architecture.

The eukaryotic nucleolus is a highly organized, multilayered structure essential for ribosomal RNA (rRNA) processing and ribosome assembly. While rRNA transcription is known to drive nucleolar assembly, the contribution of downstream processing steps to nucleolar organization remains less well defined. Here, we show th...

M. S. Mendoza-Figueroa, Ellen Lavorando, Yulia Gonskikh et al. · 0 citations
Aug 2026

PTBP1 controls oncogenic transcript processing and maintenance of acute myeloid leukemia.

Findings demonstrate that PTBP1 supports AML proliferation by fine-tuning the expression and splicing of AML-essential genes, providing a workflow for systematically annotating RNA-associated protein dependencies in cancer.

Zhendong Cao, Kurtis N. McCannell, Si-Xiang Yu et al. · 0 citations

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