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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

K. Machida

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Open access Aug 2026

SpY-C: Supervised Learning of Phosphopeptide Sequence Constraints Enables Global Prediction of SH2 Domain Binding

Tyrosine kinase signaling for cell development and homeostasis in multicelluar organisms and a major biochemical contribution is by driving interactions between phosphorylated tyrosines (pY) and SH2 domain containing proteins. This assembly is so important to driving cell outcomes that a wide variety of experimental an...

Alekhya Kandoor, A. C. Silva Oliveira, K. Machida et al. · 0 citations

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