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Author

K. Mouzat

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Open access Sep 2026

Data-driven identification of repurposable drugs for ALS

Amyotrophic lateral sclerosis (ALS) is a severe disease that causes thousands of deaths annually. Current treatments are either limited in effectiveness or not broadly applicable. To discover new options, we conducted a genetics-based screen to identify drugs that could be repurposed for ALS. We analyzed genome-wid...

S. Saez-Atienzar, Luis A. Rojas-Colón, Ruth Chia et al. · 0 citations
Open access Aug 2026

Towards routine genetic testing of repeat expansions in neurogenetic diseases using multiplex CRISPR-Cas9-targeted long read sequencing

This work evaluated CRISPR-Cas9-mediated target enrichment coupled to Oxford Nanopore Technologies (ONT) long read sequencing, to accelerate and improve the time-consuming molecular diagnosis of repeat expansion disorders.

P. Fergelot, C. Boury, B. Penaud et al. · 0 citations

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