Altered stimulus-intensity encoding occurs in the primary somatosensory cortex of a central post-stroke pain rat model.
Central post-stroke pain (CPSP) is a chronic form of pain that develops after ventral posterolateral thalamus (VPL) lesions and may involve maladaptive plasticity within central somatosensory pathways. Although abnormalities in the primary somatosensory cortex (S1) are observed in patients and animal models, the mechan...