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Author

K. Nimptsch

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Open access Oct 2026

Factors associated with the transition from health to disease for type 2 diabetes, cardiovascular disease and kidney dysfunction: A NAKO-IMMEDIATE analysis

Background: Cardio-kidney-metabolic (CKM) diseases share risk factors, but their shared and distinct risk factors for disease progression remain unclear. We examined whether classical risk factors predict baseline CKM indicators and their longitudinal changes in a population-based German National Cohort (NAKO) sample....

S. G. Chiappe, K. Nimptsch, I. M. Velásquez et al. · 0 citations
Open access Oct 2026

Exposure to childhood adversity and adult alcohol, nicotine, and illicit drug use in Germany: a cross-sectional analysis of the German National Cohort (NAKO)

Rationale Exposure to adversity in childhood and adolescence (i.e., “early-life stress”; ELS) is a well-established risk factor for substance use. Objectives The aim of this study was to investigate associations between ELS exposure and substance use across subtypes of ELS, different substance classes, and behavioral p...

J. Böhmer, Kanya Meyer-Degering, A. Ghadami et al. · 0 citations
Review Open access Oct 2026

Statistical methods for analyzing change over time of continuous outcomes in observational health studies: a scoping review of suggested approaches

A scoping review of methodological studies proposing strategies to address bias when analyzing within-person change in continuous outcomes and of applied observational studies to examine analytical practice following PRISMA guidelines and PROSPERO registration provides a structured framework to support more transparent...

M. Bouka, E. Pagkalidou, S. G. Chiappe et al. · 0 citations
Review Open access Aug 2026

Usual dietary intake estimation in the German National Cohort (NAKO)

Introduction Accurate measurement of dietary intake remains challenging in large-scale nutritional studies. This study aimed to develop and evaluate both a practical dietary assessment strategy and a computationally efficient statistical method for estimating usual dietary intake in the German National Cohort (NAKO Ges...

N. Wawro, Sylvia Gastell, R. Mikolajczyk et al. · 1 citation
Open access Sep 2026

The association of a lifestyle risk index with glycemic status in the German National Cohort (NAKO)

In this large sample of predominantly healthy adults, a combination of lifestyles, foremost driven by not smoking, was weakly associated with lower HbA1c levels but not self-reported diabetes, and lifestyle factors may be relevant for glycemic control.

G. Maskarinec, Rebecca Klapp, U. Nöthlings et al. · 0 citations

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