Author

K. Paese

3 papers indexed here

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Open access Sep 2026

Influence of Formulation Composition and Rheological Properties on the Stability of PnPP19 Peptide in Thermoresponsive Hydrogels

Peptide-based drugs present high specificity and therapeutic potential but remain limited by poor physicochemical stability, particularly in aqueous and semi-solid systems. Thermoresponsive poloxamer hydrogels have emerged as promising platforms for the formulation of peptide-based therapeutics. This study investigates...

A. Frohlich, Magali Portela Moreira, Camilla Nunes dos Reis Trindade et al. · Journal of Pharmaceutical In... · 0 citations

Open access Sep 2026

Development of Antimicrobial Chitosan-Silver and Chitosan-Gold Nanocomposite Films by 3D Printing for Skin Application

Silver (AgNP) and gold (AuNP) nanoparticles are notable in nanomedicine for their unique properties and strong antibacterial effects; however, formulating them into skin-applied systems that preserve bioactivity while controlling nanoparticle exposure remains challenging. Herein, semisolid extrusion 3D printing of chit...

Rita de Cássia dos Reis Schmidt, Vitória Espinosa de Oliveira, Tainá Griebler et al. · ACS Omega · 0 citations

Open access Aug 2026

Polymeric Drug Nanocarrier Production by Nanoprecipitation-Solvent Neutralization: A Chemically Driven Route to Rapid Solvent Removal

We report a bottom-up strategy, termed nanoprecipitation-solvent neutralization, for the preparation of drug-loaded polymeric nanospheres and nanocapsules for pharmaceutical applications. The method is compatible with hydrolysis-sensitive drug molecules and accommodates pharmaceutically approved polymers and excipien...

Gabriela Spingolon, Matheus Stecker Andrade, Daniela Lana Tommasi Schmitt et al. · ACS Applied Nano Materials · 0 citations