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Author

K. Parodi

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Open access Oct 2026

Multi-criteria proton treatment planning incorporating spot boosting for prompt gamma in-vivo range verification

Objective. Prompt gamma (PG) detection enables beam range verification and margin reduction in proton therapy, but its effectiveness is limited by counting statistics. Spot boosting has been proposed to enhance the signal-to-noise ratio by increasing the number of protons in selected spots of a pencil beam scanning tre...

Mara Schubert, Ze Huang, M. Pinto et al. · 0 citations
Open access Aug 2026

Patient-specific stopping power calibration of treatment planning x-ray CT using integrated depth-dose profiles acquired by proton transmission imaging—a feasibility study

Objective. Range uncertainties in proton therapy largely arise from the semi-empirical conversion of x-ray computed tomography (CT) Hounsfield Units to stopping power relative to water (RSP), requiring generous safety margins or robust optimization. Pencil beam-wise integrated depth-dose profiles (IDDs), obtained via p...

Ines Butz, K. Parodi, C. Gianoli · 0 citations

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