Evolutionary conservation and local structural context of DNAJC14 W576
Introduction: DnaJ heat-shock protein family (Hsp40) member C14 (DNAJC14) is an endoplasmic-reticulum-associated co-chaperone required for regulated non-structural protein 2–3 (NS2–3) processing in classical pestiviruses. Functional studies establish the importance of porcine W576, but its residue-level structural c...