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Oct 2026

The PI3K/AKT/eNOS Signaling Axis: Molecular Mechanisms and Therapeutic Implications in Cardiovascular and Metabolic Disorders

The PI3K/AKT-eNOS signalling axis - including phosphoinositide 3- kinase (PI3K)/protein kinase B (AKT)-endothelial nitric oxide synthase (eNOS) - is a crucial molecular pathway that governs vascular tone, blood circulation, glucose metabolism, and cellular survival, thereby upholding cardiovascular and metabolic ho...

Anuj Kumar Sharma, Robin Singh, R. Tiwari et al. · 0 citations
Review Sep 2026

Precision Delivery of Siponimod through Nanoemulsions: Shaping the Future of Multiple Sclerosis Management

Multiple Sclerosis (MS) is a chronic immune-mediated neurodegenerative disorder characterized by demyelination of myelin, neuroinflammatory neurons, and progressive neuronal loss. Although several disease-modifying treatments are available, some of these drugs are not easily bioavailable, cannot penetrate the Blood...

K. Ravi, K. Arora · 0 citations
Review Sep 2026

Advancement and Challenges in Multiple Sclerosis: Understanding the Disease from Etiology to Treatment.

Multiple Sclerosis (MS) is a chronic immune-mediated neurodegenerative disorder of the Central Nervous System (CNS) that affects more than 2.8 million people worldwide. It is recognized as one of the leading causes of non-traumatic neurological disability among young adults. It is an inflammatory demyelination disease...

K. Ravi, K. Arora · 0 citations

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