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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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K. Sarosiek

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Open access Sep 2026

BCL-XL dependence is a subtype agnostic actionable feature of difficult-to-treat kidney cancers

BCL-X L is a BCL-2 family anti-apoptotic protein that functions as a targetable dependency in clear cell Renal Cell Carcinoma (ccRCC), the most common form of adult kidney cancer. However, the mechanisms driving this dependence are unclear. Moreover, although significant strides have been made in managing ccRCC,...

Tupa Basuroy, Treg M. Grubb, Ananthan Sadagopan et al. · 0 citations

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