OBJECTIVES
Acute symptomatic epileptic seizures (ASySs) occur in temporal proximity to acute brain insults. Given their low risk of subsequent unprovoked seizures, current guidelines recommend either no treatment with anti-seizure medication (ASM) or early discontinuation, yet ASM treatment is often continued beyond ho...
Hannah Traben, Julia Herzig-Nichtweiß, L. Langenbruch et al.· Epilepsia· 0 citations
Importance
Concomitant use of antiseizure medications (ASMs) and direct oral anticoagulants (DOACs) is common in epilepsy, but comparative safety data remain limited.
Objective
To compare risks of thromboembolic events, major bleeding, and all-cause mortality across commonly used ASMs in adults with epilepsy receivin...
K. Schubert, C. Ferreira-Atuesta, Arunachalam Soma et al.· JAMA Neurology· 0 citations
Precision therapeutic approaches for rare neurological diseases are often hampered by a limited molecular understanding of the disease. Here, we report the first application of spatially-resolved proteomics to guide targeted treatment in a monogenic leukoencephalopathy. We investigated leukoencephalopathy with calcific...
Nils Briel, A. Köpp, Hanna Meister et al.· Brain : a journal of neurolo...· 0 citations
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