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Open access Sep 2026

Silane-Based Methyl- and Carboxyl-Functionalized Mica Substrates for High-Speed Atomic Force Microscopy

High-speed atomic force microscopy (HS-AFM) enables visualization of biomolecular dynamics in solution with high spatiotemporal resolution but requires substrates that support stable adsorption without perturbing their structure or dynamics. Mica is widely used as an HS-AFM substrate because it provides an atomically f...

Kaho Nakamoto, Yuna Goto, Sohta Yamamoto et al. · 0 citations
Preprint Aug 2026

UMEX Viewer - Software Suite for High-Speed AFM Data Analysis and Its Applications

Recent technical advances in atomic force microscopy (AFM) have led to the development of high-speed AFM (HS-AFM), which enables video-rate imaging and direct visualization of the nanoscale dynamics of biomolecules functioning in solution. Because HS-AFM rapidly generates large datasets, dedicated software is essential...

K. Umeda, Takahiro Watanabe-Nakayama, Yasuto Murayama et al. · 0 citations

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