Author

Kenneth Weke

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Review Open access Oct 2026

Mass Spectrometry Imaging-Guided Proteomics, an Emerging Frontier in Spatial Biology.

Spatial heterogeneity is a defining feature of tissue organization, yet conventional proteomic analysis provides limited information about the spatial origins of identified proteins. Spatially guided proteomics addresses this limitation by using tissue imaging techniques to select regions of interest (ROIs) for localiz...

K. Weke, J. J. Lum, D. Goodlett et al. · Mass spectrometry reviews (P... · 0 citations

Open access Aug 2026

Cell‐Type‐Resolved Proteomics Reveals Distinct Immune and Metabolic Programs Between Primary and Recurrent Ascites in HGSOC

ABSTRACT High‐grade serous ovarian carcinoma (HGSOC) frequently recurs after platinum–taxane therapy, yet recurrence‐associated changes within ascites remain unclear. We performed cell‐type‐resolved quantitative proteomics on paired ascites samples collected at primary diagnosis and at disease recurrence from three HGS...

Bo Ren, Kenneth Weke, D. Hardie et al. · PROTEOMICS - Clinical Applic... · 0 citations