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K. You

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Open access Sep 2026

Eucommia ulmoides Extract Attenuates Oxidative Stress, Endoplasmic Reticulum Stress and Apoptosis Induced by Acute Hypoxia via the Nrf2/Keap1 Pathway in Largemouth Bass (Micropterus salmoides)

Due to the hypoxic environment caused by global warming and intensive aquaculture process, fish are susceptible to oxidative damage and death. Eucommia ulmoides extract (EUE) has demonstrated antioxidant and anti-inflammatory properties. However, whether EUE can mitigate hypoxia-induced negative effects remains uninves...

K. You, Yi-Xuan Li, Wan-Qing Zhong et al. · 0 citations
Review Open access Sep 2026

Multi-Omics-Enabled Precision Strategies for Overcoming CAR-T Therapy Limitations in Gastrointestinal Malignancies.

Gastrointestinal malignancies, including gastric cancer, colorectal cancer, hepatocellular carcinoma, and pancreatic ductal adenocarcinoma, remain major causes of cancer-related morbidity and mortality worldwide. Although chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the treatment of hematologic m...

Ke Su, Zun-Yuan Tan, Han Li et al. · 0 citations
Review Open access Jul 2026

Host–Guest Interactions Govern Drug Stability and Controlled Therapeutic Release: Based on Metal–Organic Frameworks as Smart Platforms

This review focuses on stimuli‐responsive and novel MOF systems that can deliver drugs in response to pH, redox reactions, enzymes, light, magnetic fields, and other biological stimuli to treat diseases.

Rui Hua, K. You, Qifang Liu et al. · 0 citations

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