Author

K. Zengler

2 papers indexed here

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Open access Oct 2026

Targeting catecholate siderophore systems enables precision depletion of gut enterobacteria during colitis

These findings establish catecholate siderophore-mediated iron acquisition as a therapeutic target in AIEC and provide proof-of-principle that virulence-targeted immunization can selectively antagonize a disease-associated bacterium while preserving the gut microbiota.

Grant J. Norton, Anna M. Dudek, R. Gerner et al. · bioRxiv · 0 citations

Open access Sep 2026

Synthesis-driven reverse metabolomics reveals 3-hydroxy N-acyl amides as gut microbial molecules

ABSTRACT 3-Hydroxy N-acyl amides are bioactive lipids with reported anti-obesity and glucose-regulating effects, yet they are rarely detected in untargeted metabolomics studies because they are largely absent from existing spectral reference libraries. To address this gap, we synthesized an MS/MS spectral resource comp...

Victoria Deleray, Vincent Charron-Lamoureux, Kyle Vittali et al. · mSystems · 0 citations