Jul 2026
Exploring the Mechanisms of the Yueju Pill for ALD by Integrating UPLC-QE Orbitrap-MS/MS, Network Pharmacology, and Experimental Verification.
YJP intervention significantly reduced serum TG, AST, and ALT levels, alleviated hepatic lipid deposition and collagen deposition, improved liver mitochondrial homeostasis, and decreased hepatic HIF-1α expression, reflecting a therapeutic mechanism involving coordinated regulation of the gut-liver axis.
Kai-Xuan Zhou, Xiaoyong Yuan, Xiaotian Fan et al.
· Biomedical chromotography · 0 citations