An adenovirus-based mucosal vaccine induces cross-neutralizing antibodies and protects against lethal H5N1 infection in ferrets
H5N1 highly pathogenic avian influenza (HPAI) has been detected in multiple animal species, including humans, posing a significant threat to public health. Vaccines capable of eliciting robust mucosal and systemic immunity are needed to protect against HPAI infection. First- and second-generation non-replica...