Immunoinformatics-based design and in silico evaluation of a multi-epitope vaccine candidate against Naegleria fowleri.
Primary amoebic meningoencephalitis (PAM) is caused by Naegleria fowleri, a free-living amoeba. It is a fatal infection with more than 95% mortality rate. Even though several combinations of antimicrobial agents were used to treat the condition, the overall survival remains poor and no effective vaccine is currently av...