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Review Open access Oct 2026

Beyond marker expression: An ESC-informed framework for engineering and validating chicken induced pluripotent stem cells

The chicken induced pluripotent stem cells (iPSCs) are still plagued by limitations such as low reprogramming efficiency, instability, and a lack of demonstrated germline competence, which are in part attributed to the absence of a precisely defined biological pluripotency reference. In this review, we propose an ESC-i...

Usama Abdullah, Umar Sajid Kayani, M. Niaz et al. · 0 citations
Review Open access Oct 2026

High-throughput sequencing reshapes chicken sex determination and differentiation: From candidate genes to hierarchical regulatory networks.

Chicken sex determination and differentiation have long lacked a highly integrated and hierarchically defined framework comparable to the mammalian SRY-SOX9 paradigm. This is partly attributable to avian-specific biological features, including the ZZ/ZW sex chromosome system, incomplete dosage compensation, and cell-au...

Xiao-Qian Lv, Xu Tan, Qiang Wei et al. · 0 citations

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