Author

Kai-Lei Shi

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Open access Sep 2026

Myf5 Progenitors Define the Lineage Identity of Somitic Vascular Smooth Muscle Cells

Vascular smooth muscle cell (VSMC) heterogeneity drives region-specific aortic pathologies, yet the roles of somite-derived lineages remain unclear. Utilizing Myf5 and MyoD lineage tracing alongside a smooth muscle-specific Myf5 conditional knockout model, we show that Myf5-derived cells selectively populate the thorac...

Dong-Hua Hu, Kun Chen, Xi-Feng Chang et al. · International Journal of Mol... · 0 citations

Jul 2026

Causal Associations and Potential Mediating Factors Between Sarcopenia-related Traits and Heart Failure Risk: A Mendelian Randomization Study.

It is suggested that genetically predicted increased WP exerts beneficial effects against HF, partially mediated by obesity and sedentary habits, and targeting weight management and anti-sedentary interventions may mitigate HF risk in individuals with sarcopenia-related characteristics.

Yaping Zhang, Han Xu, Xinkai Qu et al. · The Cardiology · 0 citations