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Kai-Rui Wan

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Review Open access Oct 2026

Colorectal Cancer: Epidemiology, Risk Factors, Signaling Pathways, Clinical Features, Screening, Diagnosis, and Management

This review synthesizes current advances in CRC epidemiology, risk factors, signaling biology, clinical presentation, screening, diagnosis, and management across the care continuum, and frames CRC as a systems‐level disease in which genomic instability, epigenetic dysregulation, metabolic remodeling, tumor microenviron...

Kai-Rui Wan, Ke Tang, Ling-Long Wang et al. · 0 citations

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