High-Shielding and Colon-Targeted Insect Resin Microgels for Enhanced Probiotic Viability and Colitis Alleviation.
The in vivo functionality of oral probiotics is often compromised by their susceptibility to environmental and gastrointestinal stressors, coupled with limited mucosal retention. To overcome these challenges, we developed a smart, pH-responsive biomaterial platform based on shellac microgels (SCM), derived from a natur...