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Author

Kai Wu

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2 papers indexed here

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Review Open access Oct 2026

Targeting receptor tyrosine kinases: from molecular mechanisms to clinical therapeutics

Receptor tyrosine kinases (RTKs), constituting a major family of cell-surface transmembrane receptors, are essential for intracellular tyrosine phosphorylation and signal transduction. RTK signaling is crucial for cellular fate regulation and tissue homeostasis, and its disruption is linked to numerous diseases. Herein...

Kai Wu, Jia Ji, Ting Sun et al. · 0 citations
Open access Oct 2026

Propionate promotes CD8+ T-cell infiltration and enhances immunotherapy efficacy in colorectal cancer

Abstract Background Short-chain fatty acids (SCFAs) produced by the gut microbiota are increasingly recognized as regulators of host immunity, yet the role of individual SCFAs in shaping the tumor immune microenvironment in colorectal cancer (CRC) remains poorly defined. This study aims to investigate the role of propi...

Jing-Ying Pan, Le Tong, R. Fei et al. · 0 citations

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