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Kai-Yan Song

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Review Open access Sep 2026

Multidimensional roles and clinical significance of GATA3 in breast cancer

Background GATA-binding protein 3 (GATA3) is a pivotal transcriptional regulator during mammary gland development and serves as a core biomarker in breast cancer. Although traditionally recognized for maintaining luminal differentiation, its high mutation frequency reveals a complex, dual role in tumorigenesis. Methods...

Jun-Juan Tan, Wei-Han Chen, Kai-Yan Song et al. · 0 citations

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