Author

Kai-Ze Shen

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Aug 2026

GLUT1‐Targeted Biomimetic Parishin‐Modified Nanoselenium for Organ Protection by Reestablishing Mitochondrial Homeostasis via Anti‐inflammatory and Antioxidant Pathways

GLUT1‐targeted therapy is a promising approach for treating various diseases. However, overcoming the poor competitiveness of glucose‐analog ligands to bind glucose molecules is highly challenging. In this study, parishins isolated from Gastrodia elata are reported as high‐affinity GLUT1 ligands(‐9.859 kcal/mol for par...

Peng Tang, Siyi Ma, Xiao-Lin Zhang et al. · Advanced Healthcare Material... · 0 citations

Open access Sep 2026

Endophytic Fungi from Wild Polygala crotalarioides: Diversity, Antioxidant Capacity and Acetylcholinesterase Inhibitory Potential

Wild Polygala crotalarioides is an ethnomedicinal plant traditionally used for neurological health. Endophytic fungi associated with medicinal plants are increasingly recognized as sources of bioactive natural products; however, their diversity and biological activities in wild P. crotalarioides remain poorly understoo...

Kai-Ze Shen, Ming-Jian Xu, Xian-Chun Cai et al. · Journal of Fungi · 0 citations

Review Open access Aug 2026

Research Advances in Gastrodia elata Endophytes: Diversity, Secondary Metabolites and Pharmacological Activities

This article reviewed the research and development progress of endophytes associated with G. elata, including endophytes’ sources, biological functions, compound classification and pharmacological activities, and showed that more than 296 secondary metabolites were reported, with prominently characterized antifeedant a...

Tian-zhen Xie, Kai-Ze Shen, Wen-Jian Xia et al. · Journal of Fungi · 0 citations