Meta-analysis
Open access
Aug 2026
Efficacy and hemodynamic safety of perioperative dexmedetomidine for the prevention of postoperative delirium in elderly patients undergoing cardiac surgery: an updated systematic review and meta-analysis of randomized controlled trials
Perioperative dexmedetomidine may reduce POD incidence in selected older cardiac surgery patients, particularly when compared with selected active sedative or analgesic regimens, but the certainty of evidence was moderate, and the effect was less clear in saline/placebo-controlled trials.
Anan Li, Haopeng Wu, Kai Zhang et al.
· Frontiers in Neurology · 0 citations