Enlarged perivascular spaces are associated with more severe microstructural damage in white matter lesions among people with relapsing-remitting multiple sclerosis.
BACKGROUND AND OBJECTIVES Growing evidence has linked MRI-visible perivascular spaces (PVS) to multiple sclerosis (MS) pathogenesis. However, whether PVS are associated with increased microstructural damage in white matter lesions (WML) remains unclear. Using diffusion kurtosis imaging (DKI), we aimed to explore the as...