Author

Kai-Zhong Wang

3 papers indexed here

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Oct 2026

METTL3-Associated FOXD1 Regulation Promotes Lung Squamous Cell Carcinoma Progression: A Multimodel Experimental Approach.

Lung squamous cell carcinoma (LUSC) has limited treatment options, motivating investigation of molecular pathways that support tumor-cell growth. Forkhead box D1 (FOXD1) expression was assessed using gene expression profiling interactive analysis (GEPIA), quantitative reverse-transcription polymerase chain reaction (qR...

Quzong Deji, Danzeng Awang, Kai-Zhong Wang et al. · Journal of Visualized Experi... · 0 citations

Review Open access Sep 2026

Geno-guided targeting of ferroptosis: a multi-layered network to overcome radioresistance in lung cancer

Lung cancer is one of the most prevalent and lethal malignancies worldwide, and radiotherapy serves as a standard therapeutic modality for the management of advanced or inoperable non-small cell lung cancer. However, radioresistance remains a major obstacle that compromises therapeutic efficacy and drives tumor recurre...

Shi-Fang Sang, Guang-Chao Lv, Shi-Yun Feng et al. · Frontiers in Cell and Develo... · 0 citations

Aug 2026

Engineered tumor cell membrane-coated manganese-amplified STING nanoagonist potentiates PD-L1 blockade immunotherapy in non-small cell lung cancer.

Immune checkpoint blockade targeting the PD-1/PD-L1 axis has improved the treatment of non-small cell lung cancer (NSCLC), yet its therapeutic efficacy remains limited by insufficient antitumor immune activation. Herein, we developed a biomimetic manganese-amplified STING nanoagonist to potentiate PD-L1 blockade immuno...

Ye Guo, Shi-Yun Feng, Kai-Zhong Wang et al. · Colloids and Surfaces B: Bio... · 0 citations