Kai Zhuang

Menin orchestrates corticogenesis via regulation of chromatin accessibility and activation of EphA4 in late-born neurons.

The development of the mammalian cerebral cortex is tightly regulated by epigenetic mechanisms. However, the role of epigenetic modifications in gene regulation and their impact on neocortical function remain poorly understood. Here, we demonstrate that Menin, encoded by the multiple endocrine neoplasia type 1 (Men1) g...