Author

Kaige Chen

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Review Open access Aug 2026

Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders

This review discusses the conceptual evolution of AbTACs and classifies current platforms according to scaffold architecture and engineering strategies, which link target binding to intracellular routing and subsequent clearance.

Kaige Chen, Quan-Yin Hu · Advancement of science · 0 citations