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Kairui Qiu

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Review Aug 2026

From biology to therapy: advances in progranulin-related neurodegenerative diseases

A lysosome-centered framework for understanding PGRN-related neurodegenerative pathologies is presented, and TMEM106B is discussed as a critical genetic modifier within this lysosomal network, highlighting its role in shaping disease risk and phenotypic heterogeneity.

Sixian Hu, Kairui Qiu, Fangyuan Zhen et al. · 0 citations