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Kalpana Rajanala

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Review Open access Aug 2026

Retinoic acid-related orphan receptor alpha (RORα) as a candidate multi-pathway target in Alzheimer’s disease: mechanisms and therapeutic prospects

The development of Alzheimer disease (AD) involves a cluster of pathogenic processes, including amyloid-beta (Aβ) deposition, tau-mediated neurodegeneration, chronic neuroinflammation, oxidative stress (OS), metabolic dysregulation, and disruption of circadian rhythms. Nuclear hormone receptor, Retinoic Acid-Related Or...

Shivakanth Chintalapally, Kalpana Rajanala, Arun Upadhyay · 0 citations

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