Stepwise Synthesis and Mult spectroscopic Characterization of a 4-Hydroxyphenyl-Functionalized Benzimidazole Bis-Imine and Its Bis(thiazolidin-4-one) Derivative
A para-hydroxyphenyl-functionalized benzimidazole sequence was prepared through two consecutive carbonyl–amine condensations followed by thioglycolic-acid-mediated cyclization. 4-(1H-Benzimidazol-2-yl)aniline (K1) was condensed with 4-aminoacetophenone to give the amino-ketimine K2, and the remaining para-amino group w...