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Author

Kanak Parmar

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Open access Oct 2026

Plasma nucleosome profiling reports on tumor burden and molecular subtypes in small cell lung cancer

BACKGROUND Small-cell lung cancer (SCLC) is an aggressive malignancy with a poor prognosis and marked transcriptional heterogeneity that may drive distinct therapeutic vulnerabilities. Clinical translation of molecular subtyping has been limited by restricted access to tumor biopsies, particularly at relapse. METHODS W...

Gavriel Fialkoff, N. Takahashi, Israa Sharkia et al. · 0 citations
Open access Aug 2026

Spatially Organized Tertiary Lymphoid Structures Emerge in Small Cell Lung Cancer and Associate with Improved Survival

This represents one of the first spatially resolved analyses of TLS-like immune architecture in SCLC, demonstrating that organized lymphoid immunity can emerge in this classically immune-evasive disease and is associated with improved survival.

Yingying Cao, M. Nirula, Paul Mallory et al. · 0 citations

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