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Author

Kaneyasu Nishimura

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Jul 2026

Down syndrome-associated trisomic chromosomal regions modify amyloid-β accumulation and cause early death in a mouse model of aspects of Alzheimer's disease

The trisomic region in Ts1Kei mice is suggested to harbor genes associated with decreased Aβ accumulation, and the trisomic region in Ts1Rhr mice contains genes suppressing sudden death in APPswe/PS1dE9 mice.

Keiichi Ishihara, Haruka Yasui, Koki Harada et al. · 1 citation

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