Author

Kang-Kang Liu

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Open access Sep 2026

Isocyanate‐Modified Melatplatin(IV) Enhances Antitumor Efficacy via TCF4/COL6A3‐Mediated Extracellular Matrix Remodeling and cGAS‐STING Pathway Activation in Bladder Cancer

ABSTRACT Cisplatin (CDDP) chemosensitivity and severe toxicity severely limit its clinical application in muscle‐invasive bladder cancer (MIBC) and non‐muscle‐invasive bladder cancer (NMIBC). To address these unmet clinical needs, we synthesized a series of melatonin‐conjugated platinum(IV) prodrugs functionalized with...

Lin-Hui Wang, Xiao-Meng Liu, Tao Zhu et al. · Advancement of science · 0 citations

Aug 2026

Biomimetic Phytic Acid–Metal–Albumin Nanocomplexes for Tumor-Selective, Bioclearable Theranostics

A biomimetic phytic acid–metal–albumin nanoternary complex is introduced that repurposes the body’s natural PA–metal–protein assembly/clearance axis to enable tumor-targeted theranostics and unifies imaging, therapy, and immune modulation, advancing precision oncology with strong translational potential.

Dengyi Duan, Jing Peng, Wen-Yi Zhang et al. · ACS Nano Medicine · 0 citations