BACKGROUND
Early-onset atrial fibrillation (AF) patients exhibit heterogeneous comorbidity profiles, but they have long been overlooked.
OBJECTIVE
To identify comorbidity phenotype clusters in younger AF patients and evaluate prognosis and effectiveness of holistic or integrated care management based on the Atrial fi...
ABSTRACT Background: Cardiac fibrosis is a central driver of adverse remodeling and heart failure (HF), yet effective antifibrotic therapies remain limited. SerpinA3, a member of the serine protease inhibitor family, has been implicated in cardiovascular disease, but its functional role and underlying mechanisms in car...
Hui Wang, Jie Cui, Chun-Lu Huang et al.· Advancement of science· 0 citations
Background Beta-blocker (BB) benefits after acute myocardial infarction (AMI) may differ by heart failure (HF) phenotype in the contemporary reperfusion era. Objectives The authors evaluated associations of in-hospital BB therapy with 1-year outcomes after AMI complicated by HF, stratified by left ventricular ejection...
Patients can experience acute myocardial infarction (AMI) despite documented prior statin exposure, indicating persistent residual cardiovascular risk. The prognostic relevance of lipoprotein(a) [Lp(a)] and residual inflammation in this setting remains unclear.
This retrospective multicentre cohort study i...
