The Protective and Anti-fibrotic Properties of Genistein in a Rat Model of Cirrhosis and Liver Cancer.
IntroductionHepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, particularly in patients with cirrhosis. Genistein (GEN), a tyrosine kinase inhibitor with a favorable safety profile, has potential as a chemoprotective agent in high-risk populations. This study evaluated the effects...