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Author

Karem Ruiz-Araujo

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Open access Jul 2026

Integrated meta-analysis of human astrocytes transcriptomes reveals a candidate recurrent inflammatory signature in response to inflammatory and immune stimuli

The consistent upregulation of DDX58 and IFIH1 across varied inflammatory stimuli suggests that astrocytes transition into a common ‘reactive’ state that may contribute to chronic neuroinflammation, underscores the dual protective and pathological roles of astrocytes in inflammatory processes.

Andrea Luque-Bolivar, Karem Ruiz-Araujo, A. Aristizábal-Pachón et al. · 0 citations

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